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无水氯化镥

无水氯化镥名称

[ CAS 号 ]:
10099-66-8

[ 中文名 ]:
氯化镥(III)

[ 英文名 ]:
Lawrencium trichloride

[英文别名 ]:

无水氯化镥物理化学性质

[ 密度 ]:
3.98

[ 熔点 ]:
905ºC

[ 分子式 ]:
Cl3Lu

[ 分子量 ]:
281.326

[ 精确质量 ]:
279.847351

[ LogP ]:
2.06850

[ 外观性状 ]:
无色晶体

[ 储存条件 ]:
室温,干燥

无水氯化镥MSDS

无水氯化镥毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OK8400000
CHEMICAL NAME :
Lutetium chloride
CAS REGISTRY NUMBER :
10099-66-8
LAST UPDATED :
199701
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
Cl3-Lu
MOLECULAR WEIGHT :
281.32
WISWESSER LINE NOTATION :
LU G3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
7074 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EQSSDX Environmental Quality and Safety, Supplement. (Stuttgart, Fed. Rep. Ger.) V.1-5, 1975-76. Discontinued. Volume(issue)/page/year: 1,1,1975
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
315 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - ataxia Behavioral - muscle contraction or spasticity
REFERENCE :
JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 53,1186,1964
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
161 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Lungs, Thorax, or Respiration - other changes
REFERENCE :
AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 5,437,1962 *** REVIEWS *** TOXICOLOGY REVIEW JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 54,663,1965

无水氯化镥安全信息

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
26-36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
2

[ RTECS号 ]:
OK8400000

无水氯化镥合成路线

无水氯化镥上下游产品

无水氯化镥上游产品

无水氯化镥下游产品

无水氯化镥制备

由氧化镥溶于浓盐酸,将其水溶液在水浴上蒸发、浓缩,冷却后得七水合物。然后在氯化氢气流中加热脱水得无水盐。

无水氯化镥文献

Diabody Pretargeting with Click Chemistry In Vivo.

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Radioimmunotherapy and nuclear imaging (immuno-PET/SPECT) of cancer with radiometal-labeled antibody fragments or peptides is hampered by low tumor-to-kidney ratios because of high renal radiometal re...

Bone metastasis imaging with SPECT/CT/MRI: a preclinical toolbox for therapy studies.

Bone 75 , 62-71, (2015)

Bone is one of the most common metastatic target sites in breast cancer, with more than 200 thousand new cases of invasive cancer diagnosed in the US alone in 2011. We set out to establish a multimoda...

Trans-cyclooctene tag with improved properties for tumor pretargeting with the diels-alder reaction.

Mol. Pharm. 11(9) , 3090-6, (2014)

Radioimmunotherapy (RIT) of solid tumors is hampered by low tumor-to-nontumor (T/NT) ratios of the radiolabeled monoclonal antibodies resulting in low tumor doses in patients. Pretargeting technologie...


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标题:无水氯化镥_MSDS_密度_熔点_无水氯化镥CAS号【10099-66-8】_化源网 地址:https://www.chemsrc.com/amp/cas/10099-66-8_1196524.html