AM-211 sodium结构式
|
常用名 | AM-211 sodium | 英文名 | AM-211 sodium |
|---|---|---|---|---|
| CAS号 | 1263077-74-2 | 分子量 | 522.49100 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C27H26F3N2NaO4 | 熔点 | N/A | |
| MSDS | N/A | 闪点 | N/A |
AM-211 sodium用途AM-211 sodium is a novel and potent antagonist of the prostaglandin D2 receptor type 2. AM-211 is active in animal models of allergic inflammation. AM211 has high affinity for human, mouse, rat, and guinea pig DP2 and it shows selectivity over other prostanoid receptors and enzymes. AM211 exhibits good oral bioavailability in rats and dogs and dose-dependently inhibits 13,14-dihydro-15-keto-PGD(2)-induced leukocytosis in a guinea pig pharmacodynamic assay. |
| 英文名 | sodium,2-[3-[2-[[benzylcarbamoyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-4-methoxyphenyl]acetate |
|---|---|
| 英文别名 | 更多 |
| 分子式 | C27H26F3N2NaO4 |
|---|---|
| 分子量 | 522.49100 |
| 精确质量 | 522.17400 |
| PSA | 85.19000 |
| LogP | 4.60950 |
| AM-211 sodium |
| UNII-8SV621U288 |
