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Unveiling the 6,8-Rearrangement in 8-Phenyl-5,7-dihydroxyflavylium and 8-Methyl-5,7-dihydroxyflavylium through Host–Guest Complexation
10.1002/ejoc.201701009 2017-10-09 6,8-Rearrangement of the compounds 8-phenyl-5,7-dihydroxyflavylium and 8-methyl-5,7-dihydroxyflavylium is not observed at pH 1. However, the 6,8-rearrangement could be investigated by extending these studies to the moderately acidic region, in particular in t... |
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Hydrogen-Bonding Amidoindoles in the Presence of Anions: An X-ray Structure of a Receptor at the Acid–Base Half-Equivalence that Binds an Anion
10.1002/ejoc.201701040 2017-10-09 Hydrogen-bonding catalysts are shown to interact with anions through binding or an acid–base reaction. The X-ray structure reveals that at the half-equivalence point two receptors bind a PF6– anion. HBD = hydrogen-bond donor. |
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Superacid-Promoted Synthesis of CF3-Indenes Using Brominated CF3-Enones
10.1002/ejoc.201701085 2017-10-09 Transformations of 3-bromo- and 3,4-dibromo CF3-enones in superacids (FSO3H, TfOH) lead to various CF3-indenes in good yields. |
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Tandem Ring Opening/Cyclization of trans-2-Aryl-3-nitrocyclopropane-1,1-dicarboxylates with 2-Aminopyridines: Access to Pyrido[1,2-a]pyrimidin-4-one Derivatives
10.1002/ejoc.201700765 2017-10-09 trans-2-Aryl-3-nitrocyclopropane-1,1-dicarboxylates undergo tandem ring opening/cyclization with 2-aminopyridines in water to afford pyrido[1,2-a]pyrimidin-4-one derivatives. |
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Directing the Cation Recognition Ability of Calix[4]arenes toward Asymmetric Phase-Transfer Catalysis
10.1002/ejoc.201700912 2017-10-09 The recognition abilities of chiral calixarene hosts toward alkali cation guests have been exploited for the first time in asymmetric phase-transfer (PT) catalysis. The binding affinities of a series of α-methylbenzylamine-derived calix[4]arene-amides toward ... |
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Stereoselective Synthesis of Trisubstituted Epoxides Marks the Route to Chiral Building Blocks with Quaternary Centers
10.1002/ejoc.201701148 2017-10-09 Q-genic epoxidation! The stereoselective epoxidation of activated ketones affords optically active trisubstituted epoxides and a route to chiral sp3-rich building blocks supporting a quaternary center. |
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Synthesis of cis- and trans-Configured Octahydroperylenes
10.1002/ejoc.201701218 2017-10-09 The formation of octahydroperylenes by dimerization leads to the thermodynamically significantly less stable trans isomer, which can be transformed into the cis isomer in a two-step process. |
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Brønsted Acid Catalyzed Domino Aza-Piancatelli Rearrangement/Michael Reaction: Construction of 1,4-Benzodiazepin-5-ones in One Pot
10.1002/ejoc.201700957 2017-10-09 A facile one-pot method has been developed for the construction of 1,4-benzodiazepin-5-ones through a Brønsted acid catalyzed domino aza-Piancatelli rearrangement/Michael reaction between furfuryl carbinols and o-aminobenzamides under mild conditions. |
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One-Pot Synthesis of 2-(Aryl/Alkyl)amino-3-cyanobenzo[b]thiophenes and Their Hetero-Fused Analogues by Pd-Catalyzed Intramolecular Oxidative C–H Functionalization/Arylthiolation
10.1002/ejoc.201700963 2017-10-09 An efficient one-pot synthesis has been developed for substituted 2-(aryl/alkyl)amino-3-cyanobenzo[b]thiophenes and their hetero-fused analogues by using (hetero)arylacetonitriles and aryl/alkyl isothiocyanates in a PdII-catalyzed C–H functionalization/arylth... |
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Efficient Synthesis of Highly Functionalized Spirocarbocyclic Oxindoles through Hauser Annulation
10.1002/ejoc.201701023 2017-10-09 A new class of biologically important spiro[indoline-3,2′-naphthalene] was synthesized by using a Hauser annulation between methyleneindolinones and arylsulfonylphthalides catalyzed by cesium carbonate. |