|
PLGA-based nanofibers with biomimetic polynoradrenaline sheath for rapid in vivo sampling of tetrodotoxin and sulfonamides in pufferfish
10.1039/C8TB00757H 2018-04-11 Nanomaterials have shown great potential for the application in microextraction due to their distinguished nanoscale architectures and superior physicochemical properties. Herein, a novel poly(lactic-co-glycolic acid) (PLGA) solid-phase microextraction (SPME)... |
|
|
Organic nanoparticles with ultrahigh quantum yield and aggregation-induced emission characteristics for cellular imaging and real-time two-photon lung vasculature imaging
10.1039/C8TB00386F 2018-04-11 Fluorescent organic nanoparticles based on small molecules have emerged as an attractive class of fluorescent agents for bioimaging in recent years. Herein, we report an orange light-emitting BTPEBD based organic nanoparticles (BTPEBD NPs) with a large Stokes... |
|
|
Energy Transfer-based Biodetection using Optical Nanomaterials
10.1039/C8TB00614H 2018-04-11 Energy transfer-based biosensing is one of the most effective methods for fast and accurate biodetection. By designing appropriate energy transfer pairs as optical probes, a large diversity of analytes, ranging from small molecules to viruses, can be detected... |
|
|
A BODIPY disulfonate near-infrared fluorescence-enhanced probe: synthesis, high selectivity to endogenous glutathione and two-photon fluorescent turn-on through thiol-induced SNAr substitution
10.1039/C7TB03321D 2018-04-11 A novel BODIPY disulfonate BODIPY-diONs with two-photon fluorescent turn-on effect has been developed as fluorescence probe for selective detection of glutathione over cysteine and homocysteine. BODIPY-diONs is weakly fluorescent due to the 2, 4-dinitrobenzen... |
|
|
Functional aza-boron dipyrromethenes for subcellular imaging and organelle-specific photodynamic therapy
10.1039/C8TB00593A 2018-04-11 Two hydrophilic aza-boron dipyrromethene (aza-BODIPY) derivatives have first been designed and synthesised for subcellular imaging. With a triphenylphosphonium or morpholine substituent, these probes show high affinity towards the mitochondria or lysosomes of... |
|
|
Built-in Electric Field with Nanoscale Distinction for Cell Behavior Regulation
10.1039/C8TB00063H 2018-04-11 To mimic the electrical properties of collagen fibrils on the bone surface, a built-in nanoscale electric field is formed on the surface of a polypyrrole (PPy) coating-decorated potassium-sodium niobate (KNN) piezoceramic. With the fabrication strategy, the p... |
|
|
Hybrid nanoparticles based on chlorin e6-conjugated hyaluronic Acid/poly(L-histidine) copolymer for theranostic application of tumor
10.1039/C7TB03068A 2018-04-11 The aim of this study is to synthesize multifunctional hybrid nanoparticles composed of hyaluronic acid (HA) and poly(L-histidine) (PHS) having disulfide linkage and chlorin e6 (HAPHSce6ss) for diagnostic and therapeutic application against breast tumor cells... |
|
|
Covalent functionalization of graphene oxide with D-mannose: evaluating the hemolytic effect and protein corona formation
10.1039/C7TB02997G 2018-04-10 In this work, graphene oxide (GO) was covalently functionalized with D-mannose (man-GO) using mannosylated ethylenediamine. XPS (C1s and N1s) confirmed the functionalization of GO through the binding energies at 288.2 eV and 399.8 eV, respectively, which are ... |
|
|
Semiconductor versus graphene quantum dots as fluorescent probes for cancer diagnosis and therapy applications.
10.1039/C8TB00153G 2018-04-10 Early diagnosis of cancer is of critical importance in determining the outcome of a patient, and nanoparticulate fluorophores have been at the centre of research for such applications owing to their superior optical properties. Furthermore, the large surface ... |
|
|
Reduction-Responsive Core-Crosslinked Hyaluronic Acid-b-Poly(Trimethylene Carbonate-co-Dithiolane Trimethylene Carbonate) Micelles: Synthesis and CD44-Mediated Potent Delivery of Docetaxel to Triple Negative Breast Tumor In Vivo
10.1039/C8TB00094H 2018-04-10 Future cancer therapy relies on development of simple, selective and bioresponsive nanomedicines. Herein, we report that reduction-responsive core-crosslinked hyaluronic acid-b-poly(trimethylene carbonate-co-dithiolane trimethylene carbonate) micelles (HA-CCM... |