| 常用名 | 氧嗪酸钾 | CAS号 | 2207-75-2 |
|---|---|---|---|
| 价格 | ¥150.0/5g ¥480.0/25g ¥1200.0/100g | 纯度 | 97.0% |
| 备货期 | 2天 | 库存 | 5 kg |
| 产品详情(用途,包装等)
用途: Oxonic acid potassium salt is an inhibitor of uricase, oxonic inhibits the phosphorylation of 5-FU to 5-fluorouridine-5'-monophosphate catalyzed by pyrimidine phosphoribosyl-transferase in a different manner from allopurinol in cell-free extracts and intact cells in vitro.IC50 value: Target: On p.o. administration of 5-FU (2 mg/kg) and a potent inhibitor of 5-FU degradation to Yoshida sarcoma-bearing rats, oxonic acid (10 mg/kg) was found to inhibit the formation of 5-fluorouridine-5'-monophosphate from 5-FU and its subsequent incorporation into the RNA fractions of small and large intestine but not of tumor and bone marrow tissues [1]. Oxonic acid diet increased plasma uric acid by 80-90 micromol/l, while blood pressure was elevated only in hyperuricemic 5/6 nephrectomy rats (18 mmHg) [2]. 物理化学性质: CAS号:2207-75-2 常用中文名:氧嗪酸钾 常用英文名:Potassium oxonate 分子式:C4H2KN3O4 分子量:195.175 密度:N/A 沸点:N/A 熔点:300 °C(lit.) 闪点:N/A 储存条件:Refrigerator, Under Inert Atmosphere |