Bivalirudin
更新时间：2026-05-24 16:53:56
| 常用名 | 比伐卢定 | CAS号 | 128270-60-0 |
|---|---|---|---|
| 价格 | $99.89/10mg $1692.0/1g | 纯度 | 99.21% |
| 备货期 | 3天 | 库存 | 现货 |
| 产品网页 | http://www.zhaokebio.com | ||
| 产品详情（用途，包装等）
Bivalirudin is a synthetic 20-amino acid peptide and a direct thrombin inhibitor used as an anticoagulant in percutaneous coronary intervention (PCI) and for the treatment of heparin-induced thrombocytopenia (HIT). It consists of a hirudin-like N-terminal domain that binds to thrombin's active site and a C-terminal domain that interacts with the fibrinogen recognition exosite, providing rapid and predictable anticoagulation with a short half-life. Product Highlights: 1. Direct Thrombin Inhibition-Directly inhibits both free and clot-bound thrombin without requiring antithrombin III cofactor, providing rapid onset anticoagulation. Predictable anticoagulant effect with minimal patient variability; no routine monitoring required (unlike heparin). 2. Short Half-Life Advantage-Plasma half-life of only ~25 minutes with enzymatic degradation and renal clearance; anticoagulant effect dissipates within 1-2 hours of stopping infusion. Rapidly reversible anticoagulation reduces bleeding risk; ideal for procedures where fast hemostasis is needed. 3. HIT Treatment Standard HIT-FDA-approved for heparin-induced thrombocytopenia (HIT) and HIT with thrombosis syndrome (HITTS) where heparin is contraindicated. Fills critical gap in anticoagulation for HIT patients; avoids cross-reactivity with heparin-PF4 antibodies. 4. PCI Procedural Efficacy PCI-Demonstrated non-inferiority to heparin in percutaneous coronary intervention (PCI) with reduced bleeding complications in REPLACE-2 trial. Growing adoption in interventional cardiology for PCI anticoagulation, particularly in high-risk bleeding patients. 5. Linear Peptide Simplicity-Linear 20-amino acid peptide with straightforward solid-phase synthesis and well-established analytical methods. Reliable synthesis and quality control at scale; consistent batch-to-batch reproducibility for commercial supply. 6. GMP Commercial Supply GMP-Multi-kilogram GMP manufacturing capacity with full regulatory documentation (DMF, stability data, method validation). Proven supply chain supporting global generic developers with batch records for FDA, EMA, and NMPA submissions. 7. Full-Service API Partner -Integrated supply of Bivalirudin API, impurity standards, reference materials, and thrombin inhibition assay support. End-to-end procurement reduces vendor management complexity and accelerates formulation partner time-to-market. |
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：三氟醋酸比伐卢定
- 价格： ￥411.9/10mg ￥1235.9/100mg ￥872.9/50mg ￥720.9/1ml
- 纯度：99.0%
- 备货期：1天
- 联系人：阿拉丁
2881459338
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- 广东翁江化学试剂有限公司
- 广东省 韶关市 翁源县
- 产品名：比伐卢定
- 价格： ￥2400.0/1g
- 纯度：98.0%
- 备货期：需询单
- 联系人：朱丽丹
13927877242
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13927877242
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- 苏州市森菲达化工有限公司
- 江苏省 苏州市 相城区
- 产品名：比伐卢定
- 价格： ￥需询单/200kg
- 纯度：98.0%
- 备货期：需询单
- 联系人：程经理
3912721726
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18796480002
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- 中山市迪欣化工有限公司
- 广东省 中山市 三角镇
- 产品名：比伐卢定-Bivalirudin
- 价格： ￥1000.0/1g
- 纯度：99.0%
- 备货期：需询单
- 联系人：董生
2470479589
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- 江西瑞威尔生物科技有限公司
- 江西省 吉安市 峡江县
- 产品名：比伐卢定
- 价格： ￥400.0/20mg
- 纯度：98.0%
- 备货期：1天
- 联系人：李经理
2929362908
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- 上海化源世纪贸易有限公司
- 上海市 上海市 普陀区
- 产品名：三氟醋酸比伐卢定
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：徐经理
351666998
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13311869306
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- 武汉壹加壹生物科技有限公司
- 湖北省 武汉市 江夏区
- 产品名：比伐卢定
- 价格： ￥需询单/1g ￥需询单/5g
- 纯度：98.0%
- 备货期：需询单
- 联系人：刘经理
673003916
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16602739303
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参考价格：$182/10mM*1mLinDMSO