Palmitoyl Tripeptide-1 (Pal-GHK / Matrixyl S)
更新时间：2026-05-25 10:44:13
| 常用名 | 棕榈酰三肽-1 | CAS号 | 147732-56-7 |
|---|---|---|---|
| 价格 | $48.75/100mg | 纯度 | 98.64% |
| 备货期 | 3天 | 库存 | 现货 |
| 产品网页 | http://www.zhaokebio.com | ||
| 产品详情（用途，包装等）
Palmitoyl Tripeptide-1 (INCI: Palmitoyl Tripeptide-1), also known as Pal-GHK or Biopeptide CL, is one of the most extensively researched and clinically validated signal peptides in cosmetic science. Its sequence is Pal-Gly-His-Lys-OH (N-(1-oxohexadecyl)glycyl-L-histidyl-L-lysine), with a molecular weight of approximately 578.79 Da and molecular formula C30H54N6O5. Originally developed by Sederma SAS (now part of Croda International), Pal-GHK is a synthetic lipopeptide derived from the naturally occurring GHK tripeptide, a fragment of the alpha-2(I) chain of type I collagen first identified by Pickart in 1973. The palmitic acid (C16) chain was introduced to dramatically increase lipophilicity -- by 100 to 1000-fold -- enabling efficient penetration through the lipid-rich stratum corneum to the dermis where fibroblasts reside. Pal-GHK functions as a matrikine signal peptide that mimics collagen breakdown fragments. When fibroblasts detect the GHK sequence, they interpret it as evidence of collagen degradation and respond by upregulating synthesis of new ECM components through the TGF-beta signaling pathway. In vitro studies show that at 0.5 muM, Pal-GHK increases collagen I synthesis by up to 100% in human dermal fibroblasts. Clinical studies demonstrate progressive improvement: 23% wrinkle depth reduction at 4 weeks, 44.9% at 8 weeks, and up to 68% at 6 months. Skin elasticity improved by 18.81%, hydration by 28.12%, and collagen production by 54.99% after 12 weeks. |
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：棕榈酰三肽-1
- 价格： ￥597.9/250mg ￥1018.9/1g ￥需询单/1g ￥需询单/1g
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
2881459338
复制
- 广东翁江化学试剂有限公司
- 广东省 韶关市 翁源县
- 产品名：棕榈酰三肽-1
- 价格： ￥400.0/50mg
- 纯度：98.0%
- 备货期：需询单
- 联系人：朱丽丹
13927877242
复制
13927877242
复制
- 中山市迪欣化工有限公司
- 广东省 中山市 三角镇
- 产品名：棕榈酰三肽-1
- 价格： ￥810.0/1000kg
- 纯度：98.0%
- 备货期：3天
- 联系人：董生
2470479589
复制
- 上海化源世纪贸易有限公司
- 上海市 上海市 普陀区
- 产品名：N2-[N-[N-(1-氧代十六烷基)甘氨酰]-L-组氨酰]-L-赖氨酸
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：徐经理
351666998
复制
13311869306
复制
- 武汉壹加壹生物科技有限公司
- 湖北省 武汉市 江夏区
- 产品名：N-(1-氧代十六烷基)甘氨酰-L-组氨酰-L-赖氨酸
- 价格： ￥需询单/1g ￥需询单/5g
- 纯度：98.0%
- 备货期：需询单
- 联系人：刘经理
673003916
复制
16602739303
复制
查看所有供应商和价格请点击：