| 常用名 | Lethal toxin inhibitor DN1 | CAS号 | 325990-63-4 |
|---|---|---|---|
| 价格 | ¥需询单/100mg ¥需询单/250mg ¥需询单/1g | 纯度 | 98.0% |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: Lethal toxin inhibitor DN1 is a small molecule that reduces the cytotoxicity of anthrax lethal toxin (LT) an inhibitor of LT-induced pyroptosis, acts as an antagonist of GPCR receptors type-1 angiotensin II receptor (AGTR1) and apelin receptor (APLNR) with IC50 of 1.958 and 2.280 uM, respectively; protected cells irrespectively of LT concentration and reduced the pathogenicity of an additional bacterial exotoxin and several viruses, does not prevent LT internalization and catalytic activity or caspase-1 activation, also reduced the susceptibility of Drosophila melanogaster to toxin-associated bacterial infections. 物理化学性质: CAS号:325990-63-4 常用中文名:Lethal toxin inhibitor DN1 常用英文名:Lethal toxin inhibitor DN1 分子式:C14H12FN3O 分子量:257.268 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |