| 常用名 | pan-PIM inhibitor 17 | CAS号 | 1681021-52-2 |
|---|---|---|---|
| 价格 | ¥需询单/100mg ¥需询单/250mg ¥需询单/1g | 纯度 | 98.0% |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: pan-PIM inhibitor 17 is a potent, selective, orally available inhibitor of Pim kinase with IC50 of 0.8, 5.1 and 1.8 nM for Pim1, 2 and 3, respectively; disaplays broad selectivity in an internal panel of 192 kinases, only eight kinases were inhibited above 50% at 1 uM; demonstrates cellular biomarker pS6 inhibition with EC50 of 27 nM, shows tumor growth inhibition in a KG1 tumor-bearing mouse model. 物理化学性质: CAS号:1681021-52-2 常用中文名:pan-PIM inhibitor 17 常用英文名:pan-PIM inhibitor 17 分子式:C19H23ClN4O2 分子量:374.869 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |