常用名 | KS100 | CAS号 | 2408477-53-0 |
---|---|---|---|
价格 | ¥需询单/100mg ¥需询单/250mg ¥需询单/1g | 纯度 | 98.0% |
备货期 | 10天 | 库存 | 现货 |
产品详情(用途,包装等)
用途: ALDH inhibitor KS100 (KS100) is a novel, potent, multi-isoform ALDH inhibitor with IC50 of 207/1410/240 nM for ALDH1A1/ALDH2/ALDH3A1, respectively;KS100 was mitigated by development of a nanoliposomal formulation, called NanoKS100. NanoKS100 was 5-fold more selective for killing melanoma cells compared with normal human fibroblasts. Inhibition by KS100 significantly reduced total cellular ALDH activity to increase reactive oxygen species generation, lipid peroxidation, and accumulation of toxic aldehydes leading to apoptosis and autophagy. 物理化学性质: CAS号:2408477-53-0 常用中文名:KS100 常用英文名:KS100 分子式:C17H13Br2N3O2S 分子量:483.178 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |