ARN-75039
更新时间：2024-07-17 16:20:39
采购访问：16次
| 常用名 | ARN-75039 | CAS号 | 2436472-47-6 |
|---|---|---|---|
| 价格 | ￥需询单/100mg ￥需询单/250mg ￥需询单/1g | 纯度 | 98.0% |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： ARN-75039 (ARN75039) is a potent, small molecule fusion inhibitor of arenavirus, inhibits pseudotyped entry of pGTOV and pCHAPV with EC50 of 0.13 and 4.3 nM, respectively.ARN-75039 demonstrated sub-nanomolar EC50 activity against pTCRV that further translated to native wild-and NWAs, including LASV, JUNV and MACV, in pseudotyped virus assays and against native replicative LASV and JUNV.ARN-75039 also potently inhibits mutant T434I pTCRV variant with EC50 of 29 nM.ARN-75039 dramatically improved survival outcome and potently inhibited TCRV replication in serum and various tissues at doses of 10 and 35 mg/kg, provided highly significant post-exposure protection in mice against TCRV infection. 物理化学性质： CAS号：2436472-47-6 常用中文名：ARN-75039 常用英文名：ARN-75039 分子式：C27H30N2O2 分子量：414.549 密度：N/A 沸点：N/A 熔点：N/A 闪点：N/A |
上海念兴实业有限公司
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