常用名 | Cl-OCH3 | CAS号 | 2279970-72-6 |
---|---|---|---|
价格 | ¥需询单/100mg ¥需询单/250mg ¥需询单/1g | 纯度 | 98.0% |
备货期 | 10天 | 库存 | 现货 |
产品详情(用途,包装等)
用途: Cl-OCH3 is an antagonist of nuclear receptor NR4A1, decreases PD-L1 protein expression in MDA-MB-231 and 4T1 cells with EC50 of 4.4 and 4.1 uM, respectively;Cl-OCH3 decreased expression of PD-L1 mRNA, promoter-dependent luciferase activity, and protein.In in vivo studies using a syngeneic mouse model bearing orthotopically injected 4T1 cells, Cl-OCH3 decreased tumor growth and weight and inhibited lung metastasis.Cl-OCH3 also decreased expression of CD3+/CD4+/CD25+/FoxP3+ regulatory T cells and increased the Teff/Treg ratio. 物理化学性质: CAS号:2279970-72-6 常用中文名:Cl-OCH3 常用英文名:Cl-OCH3 分子式:C24H19ClN2O2 分子量:402.878 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |