| 常用名 | Rv1625c agonist V-59 | CAS号 | 958588-17-5 |
|---|---|---|---|
| 价格 | ¥需询单/100mg ¥需询单/250mg ¥需询单/1g | 纯度 | 98.0% |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: Rv1625c agonist V-59 (V-59) is a specific small molecule agonist of the Mtb adenylyl cyclase Rv1625c, inhibits Mtb growth in macrophages (EC50=0.3 uM) in an Rv1625c-dependent mechanism.V-59 inhibits Mtb growth in cholesterol media (EC50 0.70 uM), but not in media containing the two-carbon fatty acid acetate, or in standard rich growth media.V-59 stimulates Rv1625c to produce cAMP, which is necessary for V-59 to inhibit Mtb growth.Chemically activating Rv1625c via V-59 preferentially inhibits cholesterol utilization in WT Mtb, rather than equally inhibiting all lipid utilization by the bacterium. 物理化学性质: CAS号:958588-17-5 常用中文名:Rv1625c agonist V-59 常用英文名:Rv1625c agonist V-59 分子式:C17H18FN7O2 分子量:371.376 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |