常用名 | NXPZ-2 | CAS号 | 2254492-08-3 |
---|---|---|---|
价格 | ¥需询单/100mg ¥需询单/250mg ¥需询单/1g | 纯度 | 98.0% |
备货期 | 10天 | 库存 | 3 |
产品详情(用途,包装等)
用途: NXPZ-2 is an orally active Keap1-Nrf2 protein–protein interaction (PPI) inhibitor with a Ki value of 95 nM, EC50 value of 120 and 170 nM. NXPZ-2 can dose-dependently ameliorate Aβ[1-42]-Induced cognitive dysfunction, improve brain tissue pathological changes in Alzheimer’s disease (AD) mouse by increasing neuron quantity and function. NXPZ-2 can inhibit oxidative stress by increasing Nrf2 expression levels and promoting its cytoplasm to nuclear translocation, which is helpful for Keap1-Nrf2 PPI inhibitors and AD associated disease research[1]. 物理化学性质: CAS号:2254492-08-3 常用中文名:NXPZ-2 常用英文名:NXPZ-2 分子式:C27H27N5O7S2 分子量:597.66 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |