常用名 | BI 831266 | CAS号 | 958227-46-8 |
---|---|---|---|
价格 | 纯度 | 98.0% | |
备货期 | 10天 | 库存 | 现货 |
产品详情(用途,包装等)
用途: BI 831266 is a potent, selective inhibitor of Aurora kinase B (AURKB) with IC50 of binding IC50 of 42 nM; inhibits the proliferation of human non-small cell lung cancer (NSCLC), pancreatic cancer, and prostate cancer cell lines (H460 tumor cell proliferation inhibition IC50=11 nM); causes tumor regression and growth inhibition in in murine xenograft tumor models (HCT 116 colon carcinoma, BxPC3 pancreatic adenocarcinoma, and NCI-H460 NSCLC). Solid Tumors Phase 1 Clinical 物理化学性质: CAS号:958227-46-8 常用中文名:BI 831266 常用英文名:BI 831266 分子式:C27H38ClN7O2 分子量:528.098 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |