| 常用名 | 3-[(1-methyl-3-indolyl)methylidene]-2-oxo-1H-indole-5-sulfonamide | CAS号 | 622387-85-3 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: OXSI-2 is an Syk Inhibitor. OXSI-2 blocks nigericin-induced inflammasome signaling and pyroptosis independent of potassium efflux. OXSI-2 inhibits inflammasome assembly, caspase-1 activation, IL-1β processing and release, mitochondrial ROS generation, and pyroptotic cell death. Using a novel live cell potassium sensor we show that Syk inhibition with OXSI-2 has no effect on potassium efflux kinetics and that blockade of potassium efflux with extracellular potassium alters Syk phosphorylation. 物理化学性质: CAS号:622387-85-3 常用中文名:3-[(1-methyl-3-indolyl)methylidene]-2-oxo-1H-indole-5-sulfonamide 常用英文名:OXSI-2 分子式:C18H15N3O3S 分子量:353.395 密度:1.5±0.1 g/cm3 沸点:N/A 熔点:N/A 闪点:N/A 储存条件:2-8°C,密封,干燥 |