HQ-415
更新时间：2026-01-11 21:29:46
采购访问：13次
| 常用名 | HQ-415 | CAS号 | 430462-93-4 |
|---|---|---|---|
| 价格 | 纯度 | 95.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： HQ-415 is a class of clinically relevant bioactive metal chelators related to clioquinol. The effective concentration eliciting a EC50 for HQ-415 is 15 μM. IC50 value: 15 μM (EC50)in vitro: In TDP-43-expressing cells, CQ fails to synergize with HQ-161 and actually antagonizes HQ-161 rescuing activity. In contrast, despite the fact that CQ was completely inactive against TDP-43, it strongly synergized with HQ-415, decreasing the EC50 from 16 to 5 μM. HQ-415 is active in the TDP-43 model, but CQ was not HQ-161 and HQ-415 are retested in dose for their ability to rescue TDP-43. Both HQ-161 and HQ-415 rescue TDP-43 toxicity. In cells expressing α-syn, HQ-161, despite being inactive on its own, synergized with HQ-415, reducing the EC50 from 21 to 14 μM. HQ-415 strongly synergizes with CQ at multiple concentrations in cells expressing α-syn. 物理化学性质： CAS号：430462-93-4 常用中文名：HQ-415 常用英文名：HQ-415 分子式：C25H25N3O3 分子量：415.484 密度：1.2±0.1 g/cm3 沸点：614.9±55.0 °C at 760 mmHg 熔点：N/A 闪点：325.7±31.5 °C 储存条件：2-8℃ |
上海念兴实业有限公司
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- 产品名：HQ-415
- 价格：
- 纯度：95.0%
- 备货期：10天
- 联系人：徐经理
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参考价格：$462/10mM*1mLinDMSO