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alpha-1,3/4-Fucosyltransferase (α1,3/4FucT)

更新时间:2024-07-15 12:35:00 采购访问:12次

常用名 3-galactosyl-N-acetylglucosaminide 4-α-L-fucosyltransferase CAS号 37277-69-3
价格 纯度 90.0%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
This enzyme is the product of the Lewis blood group gene. Normally acts on a glycoconjugate where R (see reaction) is a glycoprotein or glycolipid. Although it is a 4-fucosyltransferase, it has a persistent 3-fucosyltransferase activity towards the glucose residue in free lactose. This enzyme fucosylates on O-4 of an N-acetylglucosamine that carries a galactosyl group on O-3, unlike EC 2.4.1.152, 4-galactosyl-N-acetylglucosaminide 3-α-L-fucosyltransferase, which fucosylates on O-3 of an N-acetylglucosamine that carries a galactosyl group on O-4. Enzymes catalysing the 4-α-fucosylation of the GlcNAc in β-D-Gal-(1→3)-β-GlcNAc sequences (with some activity also as 3-α-fucosyltransferases) are present in plants, where the function in vivo is the modification of N-glycans. In addition, the fucTa gene of Helicobacter strain UA948 encodes a fucosyltransferase with both 3-α- and 4-α-fucosyltransferase activities. Reaction: GDP-β-L-fucose + β-D-galactosyl-(1→3)-N-acetyl-D-glucosaminyl-R = GDP + β-D-galactosyl-(1→3)-[α-L-fucosyl-(1→4)]-N-acetyl-β-D-glucosaminyl-R
物理化学性质:
CAS号:37277-69-3
常用中文名:3-galactosyl-N-acetylglucosaminide 4-α-L-fucosyltransferase
常用英文名:3-galactosyl-N-acetylglucosaminide 4-α-L-fucosyltransferase
分子式:
分子量:
密度:N/A
沸点:N/A
熔点:N/A
闪点:N/A

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