1-(萘-2-基)-3-(2-氧代-2-(吡咯烷基-1-基)乙基)脲
更新时间：2024-07-15 12:32:39
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| 常用名 | N-2-萘基-N'-[2-氧代-2-(1-吡咯烷基)乙基]脲 | CAS号 | 1624117-53-8 |
|---|---|---|---|
| 价格 | 纯度 | 99.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： XY1 is a very close analogue of SGC707 (a potent, selective, and non-competitive inhibitor of PRMT3 with IC50 of 31 nM), but XY1 is completely inactive.Target: PRMT3XY1 is a close analogue of SGC707, is completely inactive againstPRMT3 at concentrations as high as 100 μM. XY1 contains a naphthyl group replacing the isoquinoline group, lacks the key hydrogen bond with T466. The naphthyl ring of XY1 could act as a weak hydrogen-bond acceptor, but this should come with a substantial enthalpic penalty. The more than 1000-fold potency loss of XY1 compared with SGC707 supports this analysis. It is unclear whether other factors such as electronic effects also contributed to the potency loss of XY1 compared with SGC707. SGC707 and XY1 are a pair of excellent tools for the biomedical community to further elucidate biological functions and disease associations of PRMT3. 物理化学性质： CAS号：1624117-53-8 常用中文名：N-2-萘基-N'-[2-氧代-2-(1-吡咯烷基)乙基]脲 常用英文名：XY1 分子式：C17H19N3O2 分子量：297.352 密度：1.3±0.1 g/cm3 沸点：514.8±42.0 °C at 760 mmHg 熔点：N/A 闪点：265.1±27.9 °C 储存条件：2-8℃ |
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- 产品名：XY1
- 价格： ￥885.9/10mg ￥144.9/1mg ￥504.9/5mg ￥1750.9/25mg
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
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N-2-萘基-N'-[2-氧代-2-(1-吡咯烷基)乙基]脲生产厂家
参考价格：$106/10mM*1mLinDMSO