| 常用名 | Collismycin A | CAS号 | 158792-24-6 |
|---|---|---|---|
| 价格 | 纯度 | 95.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: Collismycin A is a bacterial metabolite with antibacterial, antiproliferative, and neuroprotective properties. It is active against a variety of bacteria and fungi. It inhibits proliferation of A549 lung, HCT116 colon, HeLa cervical cancer cells, and NIH373 fibroblasts but not MDA-MD-231 breast cancer cells. Collismycin A forms a complex with Fe(II) and Fe(III) at a 2:1 ratio, and the addition of iron ions inhibits the antiproliferative effect of collismycin A on HeLa cells, an effect that does not occur with the addition of zinc, manganese, copper, or magnesium ions. Collismycin A (1 μM) prevents apoptosis in the brain region of zebrafish larvae by 44% in a model of neuronal cell death induced by all-trans retinoic acid. 物理化学性质: CAS号:158792-24-6 常用中文名:Collismycin A 常用英文名:Collismycin A 分子式:C13H13N3O2S 分子量:275.32600 密度:1.27g/cm3 沸点:381.2ºC at 760 mmHg 熔点:N/A 闪点:184.3ºC |