CTX0294885
更新时间：2024-07-15 12:32:06
采购访问：10次
| 常用名 | CTX-0294885 | CAS号 | 1439934-41-4 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： CTX-0294885 is a a novel bisanilino pyrimidine; exhibits inhibitory activity against a broad range of kinases in vitro, and further developed it into a Sepharose-supported kinase capture reagent.Target: Kinase capture reagentUse of a quantitative proteomics approach confirmed the selectivity of CTx-0294885-bound beads for kinase enrichment. Large-scale CTx-0294885-based affinity purification followed by LC-MS/MS led to the identification of 235 protein kinases from MDA-MB-231 cells, including all members of the AKT family that had not been previously detected by other broad-spectrum kinase inhibitors. Addition of CTx-0294885 to a mixture of three kinase inhibitors commonly used for kinase-enrichment increased the number of kinase identifications to 261, representing the largest kinome coverage from a single cell line reported to date. Coupling phosphopeptide enrichment with affinity purification using the four inhibitors enabled the identification of 799 high-confidence phosphosites on 183 kinases, ～10% of which were localized to the activation loop, and included previously unreported phosphosites on BMP2K, MELK, HIPK2, and PRKDC. Therefore, CTx-0294885 represents a powerful new reagent for analysis of kinome signaling networks that may facilitate development of targeted therapeutic strategies. 物理化学性质： CAS号：1439934-41-4 常用中文名：CTX-0294885 常用英文名：CTX0294885 分子式：C22H24ClN7O 分子量：437.925 密度：1.3±0.1 g/cm3 沸点：N/A 熔点：N/A 闪点：N/A 储存条件：-20℃ |
上海念兴实业有限公司
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主要合作伙伴：
- 上海化源生化科技有限公司
- 上海市 上海市 普陀区
- 产品名：CTX0294885
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：化源网
- 上海源溪生物科技有限公司
- 上海市 上海市 浦东新区
- 产品名：CTX0294885
- 价格： ￥需询单/1g
- 纯度：98.9%
- 备货期：1天
- 联系人：赖经理
- 上海脉铂医药科技有限公司
- 上海市 上海市 嘉定区
- 产品名：CTX0294885
- 价格： ￥1569.0/10mg ￥939.0/1g ￥1029.0/5mg ￥4649.0/5mg
- 纯度：98.0%
- 备货期：2天
- 联系人：李先生
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：CTX0294885
- 价格： ￥6385.9/100mg ￥1202.9/10mg ￥1884.9/25mg ￥3367.9/50mg
- 纯度：99.0%
- 备货期：1天
- 联系人：阿拉丁
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参考价格：$119/10mM*1mLinDMSO