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VigabatrinHydrochloride

更新时间:2024-07-15 12:31:52 采购访问:10次

常用名 Vigabatrin Hydrochloride CAS号 1391054-02-6
价格 纯度 99.0%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
Vigabatrin Hcl(γ-Vinyl-GABA; Sabril) is a structural analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) that irreversibly inhibits the catabolism of GABA by GABA transaminase.IC50 value:Target: GABA transaminaseClinical studies have shown that vigabatrin is superior to placebo in decreasing the frequency of infantile spasms. In tuberous sclerosis, vigabatrin may be considered the first-line treatment for IS. The mode of action is increasing concentrations of the inhibitory neurotransmitter GABA in the brain.A significant increase in seizure threshold was observed following systemic (i.p.) administration of high (600 or 1200 mg/kg) doses of vigabatrin. Bilateral microinjection of vigabatrin (10 μg) into either the anterior or posterior SNr also increased seizure threshold, but less markedly than systemic treatment.
物理化学性质:
CAS号:1391054-02-6
常用中文名:Vigabatrin Hydrochloride
常用英文名:Vigabatrin (Hydrochloride)
分子式:C6H12ClNO2
分子量:165.618
密度:N/A
沸点:N/A
熔点:N/A
闪点:N/A
储存条件:2-8℃

供应商信息

上海念兴实业有限公司 认证供应商

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参考价格:$66/10mM*1mLinDMSO
其他供应商价格:
2025-02-05 Vigabatrin hydrochloride
价格:¥800.9
2021-02-06 Vigabatrin Hydrochloride
价格:¥781.0

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