| 常用名 | TLR9 inhibitor 18 | CAS号 | 1351978-48-7 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: A potent, selective TLR9 antagonist with IC50 of 13 nM (human TLR9), displays 75-fold selectivity over TLR7 and no activity against TLR8 (IC50>10 uM); inhibits CpG-induced IL-6 production in mouse spleen and human PBMCs with IC50 of 74 and 244 nM, respectively; inhibits CpG-induced IL-6 production with ED50 of 0.8 mg/kg in mice, has great potential in the treatment of TLR9-mediated systemic uncontrollable inflammatory response like sepsis. 物理化学性质: CAS号:1351978-48-7 常用中文名:TLR9 inhibitor 18 常用英文名:TLR9 inhibitor 18 分子式:C25H36N6O2 分子量:452.603 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |