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Ciclesonide

更新时间:2026-01-27 13:02:54 采购访问:22次

常用名 环索奈德 CAS号 126544-47-6
价格 纯度 99.0%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
Ciclesonide(RPR251526) is a glucocorticoid used to treat obstructive airway diseases.Target: Glucocorticoid ReceptorCiclesonide (CIC) is an inhaled glucocorticosteroid. CIC (5 microM) was rapidly hydrolyzed by NHBE cells (approximately 30% conversion at 4h), with almost complete conversion by 24h. In liver and NHBE cells, major involvement of cytosolic carboxylesterases, with some contribution by cholinesterases, was indicated. The highest level of conversion was found in the liver, the site of inactivation of des-CIC through rapid oxidation by cytochrome P450. Carboxylesterases in bronchial epithelial cells probably contribute significantly to the conversion to des-CIC in the target organ, whereas low systemic levels of des-CIC are a result of the high metabolic clearance by the liver following CIC inhalation [1]. Ciclesonide may have some advantage although it is not as yet licensed in all countries for paediatric use [2].
物理化学性质:
CAS号:126544-47-6
常用中文名:环索奈德
常用英文名:Ciclesonide
分子式:C32H44O7
分子量:540.68800
密度:1.23 g/cm3
沸点:665ºC at 760 mmHg
熔点:202-209?C
闪点:210ºC
储存条件:Refrigerator

供应商信息

上海念兴实业有限公司 认证供应商

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参考价格:$106/10mM*1mLinDMSO
其他供应商价格:
2022-02-19 Ciclesonide
价格:¥597.9
2024-07-15 Ciclesonide
价格:需询单
2021-02-06 Ciclesonide
价格:¥2989.0
2023-12-13 环索奈德
价格:¥需询单
2018-04-09 环索奈德
价格:¥需询单
2018-10-24 环索奈德 126544-47-6
价格:¥需询单
2017-07-15 环索奈德
价格:¥需询单
2023-06-26 环索奈德
价格:¥需询单
2022-05-26 环索奈德
价格:¥10.0
2022-05-12 Ciclesonide
价格:$需询单

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