补骨脂酚
更新时间：2024-05-21 14:30:09
| 常用名 | 补骨脂酚 | CAS号 | 10309-37-2 |
|---|---|---|---|
| 价格 | ￥需询单/1kg ￥需询单/1g | 纯度 | 98.0% |
| 备货期 | 3天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： Bakuchiol is a phytoestrogen isolated from the seeds of Psoralea corylifolia L; has anti-tumor effects.IC50 value:Target:in vitro: Bakuchiol reduced mitochondrial membrane potential (Psim) of cells in a concentration- and time-dependent manner, showing a more potent effect than that of resveratrol. S phase arrest, caspase 9/3 activaton, p53 and Bax up-regulation, as well as Bcl-2 down-regulation were observed in bakuchiol-treated A549 cells [1]. UGT2B7 was inhibited by the strongest intensity. The noncompetitive inhibition was demonstrated by the results obtained from Dixon plot and Lineweaver-Burk plot. The Ki value was calculated to be 10.7 μM [2]. Bakuchiol was found to be naturally occurring potent inhibitors of hCE2, with low Ki values ranging from 0.62μM to 3.89μM [3]. After exposure to bakuchiol at 0.25-fold, 0.5-fold and 1-fold of minimum inhibitory concentration (MIC) (3.91 μg/ml) for 24h, the fungal conidia of T. mentagrophytes demonstrated a significant dose-dependent increase in membrane permeability. Moreover, bakuchiol at 1-fold MIC elicited a 187% elevation in reactive oxygen species (ROS) level in fungal cells after a 3-h incubation [4].in vivo: In combination with the reported concentration after an intravenous administration of bakuchiol (15 mg/kg) in rats, the high risk of in vivo inhibition of bakuchiol towards UGT2B7-catalyzed metabolism of drugs was indicated [2]. In a guinea pig model of tinea pedis, bakuchiol at 1%, 5% or 10% (w/w) concentration in aqueous cream could significantly reduce the fungal burden of infected feet (p 物理化学性质： CAS号：10309-37-2 常用中文名：补骨脂酚 常用英文名：Bakuchiol 分子式：C18H24O 分子量：256.383 密度：1.0±0.1 g/cm3 沸点：391.4±21.0 °C at 760 mmHg 熔点：N/A 闪点：176.6±11.7 °C 储存条件：通风低温干燥 |
- 上海源溪生物科技有限公司
- 上海市 上海市 浦东新区
- 产品名：Bakuchiol
- 价格： ￥需询单/1g
- 纯度：98.9%
- 备货期：1天
- 联系人：赖经理
- 上海阿摩尔生物科技有限公司
- 上海市 上海市 奉贤区
- 产品名：(S,E)-4-(3,7-二甲基-3-乙烯基辛基-1,6-二烯-1-基)苯酚
- 价格： ￥需询单/100mg ￥需询单/10mg ￥需询单/1g ￥需询单/1mg
- 纯度：96.0%
- 备货期：需询单
- 联系人：王汐瑶
- 四川恒诚致远生物科技有限公司
- 四川省 成都市 温江区
- 产品名：补骨脂酚
- 价格： ￥需询单/5mg ￥需询单/20mg ￥需询单/100mg ￥需询单/1g
- 纯度：98.0%
- 备货期：需询单
- 联系人：张半夏
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：补骨脂酚
- 价格： ￥836.0/50mg ￥372.0/10mg ￥需询单/1g ￥需询单/1g
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
- 盼得（上海）国际贸易有限公司
- 上海市 上海市 徐汇区
- 产品名：补骨脂酚
- 价格： ￥需询单/500g ￥需询单/1kg ￥需询单/25kg ￥需询单/200kg
- 纯度：0.0%
- 备货期：需询单
- 联系人：叶经理
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参考价格：￥612/5mg