(±)-ErSO

更新时间：2025-08-25 17:38:18

(±)-ErSO用途

(±)-ErSO是ErSO的外消旋体。ErSO是一种选择性预期未折叠蛋白反应(a-UPR)激活剂[1]。

英文名	(±)-ErSO

描述	(±)-ErSO是ErSO的外消旋体。ErSO是一种选择性预期未折叠蛋白反应(a-UPR)激活剂[1]。
相关类别	研究领域 >> 癌症信号通路 >> 其他 >> 其他
参考文献	[1]. Boudreau MW, et al. A small-molecule activator of the unfolded protein response eradicates human breast tumors in mice. Sci Transl Med. 2021;13(603):eabf1383.

分子式	C₂₂H₁₃F₆NO₃
分子量	453.33
InChIKey	ZFSRXAHDJSCEDS-UHFFFAOYSA-N
SMILES	O=C1Nc2c(C(F)(F)F)cccc2C1(c1ccc(O)cc1)c1ccc(OC(F)(F)F)cc1

实验名称：Selectivity ratio of IC50 for human MDA-MB-231 cells to IC50 for human MCF7 cells
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5158045

实验名称：Anticancer activity against ERalpha negative human HT-29 cells assessed as cell growt...
来源：ChEMBL
靶标：HT-29
External Id：CHEMBL5158044

实验名称：Selectivity ratio of IC50 for human HCT-116 cells to IC50 for human MCF7 cells
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5158047

实验名称：Selectivity ratio of IC50 for human MDA-MB-436 cells to IC50 for human MCF7 cells
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5158046

实验名称：Anticancer activity against ERalpha negative human HCT-116 cells assessed as cell gro...
来源：ChEMBL
靶标：HCT-116
External Id：CHEMBL5158041

实验名称：Anticancer activity against ERalpha negative human HCT-116 cells assessed as cell gro...
来源：ChEMBL
靶标：HCT-116
External Id：CHEMBL5158040

实验名称：Anticancer activity against ERalpha negative human HT-29 cells assessed as cell growt...
来源：ChEMBL
靶标：HT-29
External Id：CHEMBL5158043

实验名称：Anticancer activity against ERalpha negative human MDA-MB-231 cells assessed as cell ...
来源：ChEMBL
靶标：MDA-MB-231
External Id：CHEMBL5158037

实验名称：Anticancer activity against ERalpha negative human MDA-MB-231 cells assessed as cell ...
来源：ChEMBL
靶标：MDA-MB-231
External Id：CHEMBL5158036

实验名称：Anticancer activity against ERalpha positive human MCF7 cells assessed as cell growth...
来源：ChEMBL
靶标：MCF7
External Id：CHEMBL5158033

共34条，当前第1页，共4页