常用名 | NX-2127 | CAS号 | 2416131-46-7 |
---|---|---|---|
价格 | ¥需询单/1mg | 纯度 | 98.0% |
备货期 | 1天 | 库存 | 询单 |
产品详情(用途,包装等)
用途: NX-2127 is an orally and potent BTK inhibitor, inducing degradation of the mutated BTKC481S in cells. NX-2127 inhibits proliferation of BTKC481S mutant TMD8 cells, more effectively than Ibrutinib (HY-10997). NX-2127 catalyzes the degradation of Ikaros (IKZF1) and Aiolos (IKZF3) with of 25 nM and 54 nM, respectively. NX-2127 stimulates T cell activation and increases IL-2 production in primary human T Cells[1][2]. 物理化学性质: CAS号:2416131-46-7 常用中文名:NX-2127 常用英文名:NX-2127 分子式:C39H45N9O5 分子量:719.83 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |