Fosamprenavir calcium
更新时间：2025-09-09 17:56:49
采购访问：49次
| 常用名 | 福沙那伟钙 | CAS号 | 226700-81-8 |
|---|---|---|---|
| 价格 | ￥需询单/1g | 纯度 | 98.0% |
| 备货期 | 1天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： GW433908 is a phosphate ester prodrug of the antiretroviral protease inhibitor amprenavir, with improved solubility over the parent molecule and a potential for reduced pill burden on current dosing regimens; GW433908G is the calcium salt of the prodrug.IC50 Value:Target: HIV Proteasein vitro: There were no significant changes in buprenorphine or PI plasma levels and no significant changes in medication adverse effects or opioid withdrawal. Increased concentrations of the inactive metabolite buprenorphine-3-glucuronide suggested that darunavir-ritonavir and fosamprenavir-ritonavir induced glucuronidation of buprenorphine[1].in vivo: Fosamprenavir-ritonavir administered with methadone did not alter plasma amprenavir pharmacokinetics compared with historical control data; nor did it alter the unbound R-methadone at 2 and 6 hours after methadone dosing. Pharmacodynamic indexes remained essentially unchanged after adding fosamprenavir-ritonavir to methadone [2]. After a high-fat meal compared with fasting, (1) the bioavailability of GW433908G suspension was decreased by 20% and Cmax by 41%, and (2) for GW433908G tablets, there was no influence on AUC(12% lower Cmax). After a low-fat meal compared with fasting, (1) there was bioequivalence for GW433908G tablets, but (2) bioavailability was decreased by 23% for amprenavir capsules (Cmax was also lower, by 46%) [3].Clinical trial: Study of an Investigational Regimen Including FDA Approved HIV Drugs In HIV-Infected Pediatric Subjects. Phase 2 物理化学性质： CAS号：226700-81-8 常用中文名：福沙那伟钙 常用英文名：Fosamprenavir (Calcium Salt) 分子式：C25H34CaN3O9PS 分子量：623.669 密度：N/A 沸点：N/A 熔点：282-284ºC 闪点：N/A 储存条件：2-8℃ |
武汉敬康恩生物医药科技有限公司
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地区： 湖北省 武汉市 东西湖区
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- 上海源溪生物科技有限公司
- 上海市 上海市 浦东新区
- 产品名：Fosamprenavir calcium
- 价格： ￥需询单/1g
- 纯度：98.9%
- 备货期：1天
- 联系人：赖经理
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：福沙普列那韦钙盐
- 价格： ￥772.9/50mg ￥1122.9/100mg ￥5149.9/1g ￥1908.9/250mg
- 纯度：95.0%
- 备货期：1天
- 联系人：阿拉丁
- 武汉敬康恩生物医药科技有限公司
- 湖北省 武汉市 东西湖区
- 产品名：Fosamprenavir calcium
- 价格： ￥需询单/1g
- 纯度：98.0%
- 备货期：1天
- 联系人：周经理
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参考价格：$178/1mg