| 常用名 | 迪拉马尼 | CAS号 | 681492-22-8 |
|---|---|---|---|
| 价格 | ¥需询单/1kg ¥需询单/1g ¥需询单/1mg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情(用途,包装等)
用途: Delamanid, a newer mycobacterial cell wall synthesis inhibitor, inhibits the synthesisi of mucolic acids, cruciala component of the cell wall of the Mycobacterium tuberculosis complex.In vitro: inhibits the synthesisi of mucolic acids, cruciala component of the cell wall of the Mycobacterium tuberculosis complex.[1]In in-vitro studies, delamanid shows more potent antibacterial activity against drug-susceptible and drug-resistant strains of M. tuberculosis.[2] Delamanid do not affect rifampin, pyrazinamide, and isoniazid exposure; the ethambutol AUCτ and Cmax values are about 25% higher with delamanid coadministration. [3] In vivo: Twice-daily oral dosing of delamanid at 30 mg kg-1 for 5 days resulted in sterile cures in a mouse model of VL. [4] 物理化学性质: CAS号:681492-22-8 常用中文名:迪拉马尼 常用英文名:Delamanid 分子式:C25H25F3N4O6 分子量:534.484 密度:1.5±0.1 g/cm3 沸点:653.7±65.0 °C at 760 mmHg 熔点:N/A 闪点:349.1±34.3 °C 储存条件:-20℃ |