GW627368X
更新时间：2024-10-11 23:39:14
| 常用名 | GW627368 | CAS号 | 439288-66-1 |
|---|---|---|---|
| 价格 | ￥需询单/1kg ￥需询单/1g ￥需询单/1mg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： GW627368(GW627368X) is a novel, potent and selective competitive antagonist of prostanoid EP4 receptor(Ki= 100 nM) with additional human TP receptor affinity(Ki= 150 nM).IC50 value: Target: EP4 antagonistin vitro: At recombinant human prostanoid EP4 receptors expressed in HEK293 cells, GW627368X produced parallel rightward shifts of PGE2 concentration-effect (E/[A]) curves resulting in an affinity (pKb) estimate of 7.9 +/- 0.4. GW627368X appears to bind to human prostanoid TP receptors but not the TP receptors of other species. In human washed platelets, GW627368X (10 microM) produced 100% inhibition of U-46619 (EC100)-induced aggregation (approximate pA2 approximately 7.0) [1]. in vivo: Oral administration of GW627368X showed significant tumor regression characterized by tumor reduction and induction of apoptosis. Reduction in prostaglandin E2 synthesis also led to reduced level of VEGF in plasma [2]. 物理化学性质： CAS号：439288-66-1 常用中文名：GW627368 常用英文名：GW 627368 分子式：C30H28N2O6S 分子量：544.618 密度：1.3±0.1 g/cm3 沸点：N/A 熔点：N/A 闪点：N/A 储存条件：2-8℃ |
- 上海化源世纪贸易有限公司
- 上海市 上海市 普陀区
- 产品名：2-(4-(4,9-二乙氧基-1-氧代-1H-苯并[f]异吲哚-2(3H)-基)苯基)-N-(苯基磺酰基)乙酰胺
- 价格：
- 纯度：99.0%
- 备货期：10天
- 联系人：徐经理
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：GW 627368
- 价格： ￥2265.9/10mg ￥420.9/1mg ￥9269.9/250mg ￥4119.9/25mg
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
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参考价格：$273/10mM*1mLinDMSO