| 常用名 | APD668 | CAS号 | 832714-46-2 |
|---|---|---|---|
| 价格 | ¥需询单/1kg ¥需询单/1g ¥需询单/1mg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情(用途,包装等)
用途: APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119 respectively..IC50 value: 2.7 nM (EC50) [1]Target: GPR119Chronic treatment withAPD668 showed for the first time that blood glucose and glycated hemoglobin (HbA1c) levels could be significantly reduced in Zucker Diabetic Fatty (ZDF) rats over several weeks of dosing. APD668 was the ?rst compound with thismechanism of action to be progressed into clinical development for the treatment of diabetes. 物理化学性质: CAS号:832714-46-2 常用中文名:APD668 常用英文名:APD 668 分子式:C21H24FN5O5S 分子量:477.509 密度:1.5±0.1 g/cm3 沸点:611.6±55.0 °C at 760 mmHg 熔点:N/A 闪点:323.7±31.5 °C 储存条件:-20℃ |