WS6
更新时间：2024-09-05 19:17:30
| 常用名 | WS6 | CAS号 | 1421227-53-3 |
|---|---|---|---|
| 价格 | ￥需询单/1kg ￥需询单/1g ￥需询单/1mg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： WS6 is a novel small molecule that promotes β cell proliferation in rodent and human primary islets with EC50 of 0.28 uM(R7T1 cell viability).EC50 value: 0.28 uM [1]Target: β cell proliferation agonistin vitro: WS6 induced up to 4% of rat β cells to proliferate, with an EC50 of 0.4 μM. In the same format, WS6 also induced 3% of human β cells to proliferate, with a similar potency to the rat β cells. WS6 induced R7T1 proliferation in dose response, with EC50 value of 0.28 μM, Proliferation of R7T1 cells, which are cultured in suspension and grow as clusters, was apparent by visible inspection. in vivo: RIP-DTA mice were fed Dox in the drinking water until the onset of overt diabetes (blood glucose reading >300 mg/dL, typically 4-10 days), at which point Dox treatment was discontinued and treatment with WS6 was initiated (5 mg/kg every other day via intraperitoneal injection). Pharmacokinetic studies with WS6 at 50 mg/kg revealed a CMAX of ～5 μM and T1/2 of ～2 h. Treatment with WS6 caused a progressive reduction of blood glucose over time, starting around 2 weeks. 物理化学性质： CAS号：1421227-53-3 常用中文名：WS6 常用英文名：WS6 分子式：C29H31F3N6O3 分子量：568.590 密度：1.4±0.1 g/cm3 沸点：744.1±60.0 °C at 760 mmHg 熔点：N/A 闪点：403.8±32.9 °C 储存条件：2-8°C |
- 上海化源生化科技有限公司
- 上海市 上海市 普陀区
- 产品名：WS6
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：徐经理
- 上海源溪生物科技有限公司
- 上海市 上海市 浦东新区
- 产品名：WS6
- 价格： ￥需询单/1g
- 纯度：98.9%
- 备货期：1天
- 联系人：赖经理
- 上海脉铂医药科技有限公司
- 上海市 上海市 嘉定区
- 产品名：WS6
- 价格： ￥5200.0/100mg ￥需询单/1g ￥860.0/10mg ￥需询单/10mg
- 纯度：98.0%
- 备货期：2天
- 联系人：李先生
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：WS6
- 价格： ￥720.9/1ml ￥1463.9/100mg ￥257.9/10mg ￥2883.9/200mg
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
- 武汉敬康恩生物医药科技有限公司
- 湖北省 武汉市 东西湖区
- 产品名：WS6
- 价格： ￥需询单/1g ￥需询单/5g
- 纯度：98.0%
- 备货期：需询单
- 联系人：周经理
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参考价格：$105/10mM*1mLinDMSO