| 常用名 | Walrycin B | CAS号 | 878419-78-4 |
|---|---|---|---|
| 价格 | ¥需询单/1kg ¥需询单/1g ¥需询单/1mg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情(用途,包装等)
用途: Walrycin B is a novel antibacterial compound specifically targeting the essential WalR response regulator.IC50 value: 0.39 ug/ml (MIC for B. subtilis 168); 3.13 ug/ml (MIC for S. aureus N315) [1]Target: bacterial WalR response regulator; AntibacterialWalrycin B is known as an analog of toxoflavin (a phytotoxin from Burkholderia glumae), which has been shown to have a strong MIC for B. subtilis and S. aureus but whose mode of action is not clear. The compound could also interact with WalR to cause bactericidal effects. Walrycins are a new class of potent small molecule compounds that kill bacterial cells by targeting the RR WalR and inhibiting this essential signal transduction pathway. They not only have therapeutic potential but will also prove to be useful reagents for the further study of the WalK/WalR TCS. Walrycin B target WalR andlead to cell death in both B. subtilis and S. aureus. 物理化学性质: CAS号:878419-78-4 常用中文名:Walrycin B 常用英文名:Walrycin B 分子式:C14H10F3N5O2 分子量:337.257 密度:1.6±0.1 g/cm3 沸点:383.1±52.0 °C at 760 mmHg 熔点:N/A 闪点:185.5±30.7 °C 储存条件:-20℃ |