INH1
更新时间：2025-09-14 18:19:12
| 常用名 | N-[4-(2,4-二甲基苯基)-2-噻唑基]苯甲酰胺 | CAS号 | 313553-47-8 |
|---|---|---|---|
| 价格 | ￥需询单/1kg ￥需询单/1g ￥需询单/1mg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： INH1 is a small molecule targeting the Hec1/Nek2 mitotic pathway suppresses tumor cell growth in culture and in animal.IC50 value: 10-21 uM (GI50 in human breast cancer cell lines) [1]Target: Hec1 inhibitorTreating cells with INH1 triggered reduction of kinetochore-bound Hec1 as well as global Nek2 protein level, consequently leading to metaphase chromosome misalignment, spindle aberrancy, and eventual cell death. INH1 effectively inhibited the proliferation of multiple human breast cancer cell lines in culture (GI(50), 10-21 micromol/L). Furthermore, treatment with INH1 retarded tumor growth in a nude mouse model bearing xenografts derived from the human breast cancer line MDA-MB-468, with no apparent side effects. This study suggests that the Hec1/Nek2 pathway may serve as a novel mitotic target for cancer intervention by small compounds. 物理化学性质： CAS号：313553-47-8 常用中文名：N-[4-(2,4-二甲基苯基)-2-噻唑基]苯甲酰胺 常用英文名：INH1 分子式：C18H16N2OS 分子量：308.40 密度：1.2±0.1 g/cm3 沸点：N/A 熔点：N/A 闪点：N/A 储存条件：Desiccate at +4°C |
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：INH1
- 价格： ￥205.9/10mg ￥617.9/50mg ￥926.9/100mg ￥1596.9/250mg
- 纯度：99.0%
- 备货期：1天
- 联系人：阿拉丁
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参考价格：￥574/10mg