缬更昔洛韦盐酸盐
更新时间：2023-02-12 19:25:55
| 常用名 | 缬更昔洛韦盐酸盐 | CAS号 | 175865-59-5 |
|---|---|---|---|
| 价格 | ￥需询单/1kg | 纯度 | 99.0% |
| 备货期 | 需询单 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： Valganciclovir (hydrochloride), the L-valyl ester of ganciclovir, is actually a prodrug for ganciclovir. Valganciclovir is an antiviral medication used to treat cytomegalovirus infections.IC50 Value: Target: CMVin vitro: In cell culture model systems using Caco-2 cells for PEPT1 and SKPT cells for PEPT2, valganciclovir inhibited glycylsarcosine transport mediated by PEPT1 and PEPT2 with K(i) values (inhibition constant) of 1.68+/-0.30 and 0.043+/- 0.005 mM, respectively. The inhibition by valganciclovir was competitive in both cases [1].in vivo: 37 patients were enrolled; 19 patients received treatment with VGV and 18 patients received treatment with GCV. The VGV was not inferior in efficacy to GCV as pre-emptive therapy, with rates of viral clearance at 28 days of 89.5% and 83%, respectively (P-value for non-inferiority = 0.030). Toxicities were similar between the 2 arms. No patients developed CMV disease [2]. Patients being treated with an alemtuzumab-containing regimen received prophylaxis with either valaciclovir 500 mg orally daily orvalganciclovir 450 mg orally twice daily. None of the 20 patients randomized to valganciclovir experienced CMV reactivation (P = .004) [3]. 物理化学性质： CAS号：175865-59-5 常用中文名：缬更昔洛韦盐酸盐 常用英文名：Valganciclovir Hydrochloride 分子式：C14H23ClN6O5 分子量：390.823 密度：N/A 沸点：629.1ºC at 760 mmHg 熔点：N/A 闪点：N/A 储存条件：-20°C |
- 上海化源生化科技有限公司
- 上海市 上海市 普陀区
- 产品名：(2S)-2-((2-氨基-6-氧代-1H-嘌呤-9(6H)-基)甲氧基)-3-羟丙基2-氨基-3-甲基丁酸酯盐酸盐
- 价格：
- 纯度：99.0%
- 备货期：10天
- 联系人：徐经理
- 上海吉至生化科技有限公司
- 上海市 上海市 奉贤区
- 产品名：缬更昔洛韦盐酸盐
- 价格： ￥3508.0/250mg ￥338.0/10mg ￥998.0/50mg
- 纯度：99.0%
- 备货期：2天
- 联系人：刘佳
- 上海源溪生物科技有限公司
- 上海市 上海市 浦东新区
- 产品名：Valganciclovir (hydrochloride)
- 价格： ￥需询单/1g
- 纯度：98.9%
- 备货期：1天
- 联系人：赖经理
- 上海脉铂医药科技有限公司
- 上海市 上海市 嘉定区
- 产品名：Valganciclovir HCl
- 价格： ￥1439.0/100mg ￥789.0/1g ￥1059.0/50mg ￥需询单/1g
- 纯度：98.0%
- 备货期：2天
- 联系人：李先生
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：缬更昔洛韦盐酸盐
- 价格： ￥29.9/10mg ￥169.9/1g ￥99.9/250mg ￥39.9/50mg
- 纯度：99.0%
- 备货期：1天
- 联系人：阿拉丁
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参考价格：$145/10mM*1mLinDMSO