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(-)-3-(3,4-二羟基苯基)-2-甲基-L-丙氨酸倍

更新时间:2025-09-11 22:42:39

常用名 左旋甲基多巴 CAS号 41372-08-1
价格 ¥需询单/10mg ¥需询单/25mg ¥需询单/50mg ¥需询单/100mg 纯度 99.9%
备货期 需询单 库存 现货
 产品详情(用途,包装等)
用途:
L-(-)-α-Methyldopa hydrate is an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive drug used as a sympatholytic or antihypertensive.Target: alpha-adrenergic agonistMethyldopa is an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive drug used as a sympatholytic or antihypertensive. Its use is now mostly deprecated following the introduction of alternative safer classes of agents. However, it continues to have a role in otherwise difficult to treat hypertension and gestational hypertension (also known as pregnancy-induced hypertension (PIH)).Methyldopa has a dual mechanism of action. It is a competitive inhibitor of the enzyme DOPA decarboxylase, also known as aromatic L-amino acid decarboxylase, which converts L-DOPA into dopamine. Dopamine is a precursor for norepinephrine (noradrenaline) and subsequently epinephrine (adrenaline). This inhibition results in reduced dopaminergic and adrenergic neurotransmission in the peripheral nervous system. This effect may lower blood pressure and cause central nervous system effects such as depression, anxiety, apathy, anhedonia, and parkinsonism. It is converted to α-methylnorepinephrine by dopamine beta-hydroxylase (DBH). α-methylnorepinephrine is an agonist of presynaptic central nervous system α2-adrenergic receptors. Activation of these receptors in the brainstem appears to inhibit sympathetic nervous system output and lower blood pressure. This is also the mechanism of action of clonidine.
物理化学性质:
CAS号:41372-08-1
常用中文名:左旋甲基多巴
常用英文名:Methyldopa Sesquihydrate
分子式:C10H13NO4.3/2H2O
分子量:238.24
密度:1.4±0.1 g/cm3
沸点:441.6±45.0 °C at 760 mmHg
熔点:>300 °C(lit.)
闪点:220.9±28.7 °C
储存条件:Refrigerator

供应商信息

深圳菲斯生物科技有限公司

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地址:广东省深圳市龙华区民治街道民康路292号青创城D栋3A1
地区: 广东省 深圳市 龙岗区
联系人:王晓红
联系人电话:13380397412
邮件:2843428289@qq.com
网址:http://www.phystandard.com.cn/
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深圳菲斯生物科技有限公司成立于2012年,是一家基于化学和医药科技基础的高科技企业。公司致力于新药及仿制药注册申报用药物标准品、杂质对照品的生产、研发和销售,承接杂质对照品的定制服务、未知杂质分析、分离纯化服务,同时提供参比制剂一次性进口、化学试剂、实验室耗材等,是集研发、生产、销售为一体的医药科技企业。
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参考价格:$66/10mM*1mLinDMSO
其他供应商价格:
2024-07-15 L-甲基多巴水合物
价格:需询单
2019-03-05 P-甲苯甲酸苯酯, 99%
价格:¥168.0
2022-11-29 L-Methyldopa
价格:¥需询单
2022-02-19 Methyldopa Sesquihydrate
价格:¥194.9
2017-04-21 L-甲基多巴
价格:¥300.0
2018-01-09 甲基多巴
价格:¥需询单
2018-11-09 左旋甲基多巴
价格:¥需询单
2023-02-20 (-)-3-(3,4-二羟基苯基)-2-甲基-L-丙氨酸 倍半水合物, 99%
价格:¥159.0
2024-01-09 Better of alpha-Methyldopa sesquihydrate
价格:$需询单

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