YHV98-4

更新时间：2024-07-17 15:06:32 采购访问：14次

常用名	N-(4-chlorophenyl)-2-(3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazin-2-yl)acetamide	CAS号	132858-26-5
价格	$需询单/100mg $需询单/250mg $需询单/1g	纯度	98.0%
备货期	3天	库存	3
产品网页	https://www.dcchemicals.com/product_show-yhv98-4.html

产品详情（用途，包装等） YHV98-4 is a selective inhibitor of proton-selective ion channel Hv1 with IC50 of 0.7 uM; YHV98-4 displays no inhibitory effects against other channels containing VSDs, including hERG, KCNQ2, BK, and Nav1.7 channel. YHV98-4 did not inhibit transient receptor potential V1 (TRPV1) or A1 (TRPA1) at 20 uM, which also contains VSD-like domain. YHV98-4 restores impaired ROS-mediated inflammatory pathway, restores impaired ROS-SHP-1-PI3K/pAKT-CXCL1 pathway and attenuates morphine-induced hyperalgesia and tolerance.

DC Chemicals Limited

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