常用名 | SBI-0637142 | CAS号 | 1612927-67-9 |
---|---|---|---|
价格 | $需询单/100mg $需询单/250mg $需询单/1g | 纯度 | 98.0% |
备货期 | 3天 | 库存 | 3 |
产品网页 | https://www.dcchemicals.com/product_show-sbi-0637142.html |
产品详情(用途,包装等)
SBI-0637142 is a potent Smac mimetic that preferentially targets BIRC2, latency-reversing agent (LRA), specifically and potently promote HIV-1 latency reversal activity.SBI-0637142 modestly induced HIV-1 latency ex vivo in CD4+ T cells from ART-suppressed aviremic HIV-infected patients as a single agent, showed robust activity when administered in combination with the HDACi panobinostat.SBI-0637142's latency reversal activity is dependent on the NIK-dependent NF-κB signaling. |