| 常用名 | JH-X-119-01 | CAS号 | 2227368-54-7 |
|---|---|---|---|
| 价格 | ¥650.0/100mg ¥1250.0/250mg ¥2500.0/1g | 纯度 | 98.0% |
| 备货期 | 1天 | 库存 | 3 |
| 产品网页 | https://www.dcchemicals.com/product_show-DC60125.html | ||
| 产品详情(用途,包装等)
Jh-X-119-01 is a novel potent and selective interleukin-1 receptor-associated kinases 1 (IRAK1) inhibitor. JH-X-119-01 irreversibly labels IRAK1 at C302. This compound exhibited cytotoxic activity at single digit micromolar concentrations in a panel of WM, DLBCL, and lymphoma cell lines expressing MYD88. Cotreatment of JH-X-119-01 with the BTK inhibitor ibrutinib resulted in synergistic killing effects in these systems. |