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Valganciclovir

更新时间:2025-09-08 18:52:44 采购访问:35次

常用名 缬更昔洛韦 CAS号 175865-60-8
价格 $需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg 纯度 98.0%
备货期 需询单 库存 询单
 产品详情(用途,包装等)
用途:
Valganciclovir, the L-valyl ester of ganciclovir, is actually a prodrug for ganciclovir. Valganciclovir is an antiviral medication used to treat cytomegalovirus infections.IC50 Value: Target: CMVin vitro: In cell culture model systems using Caco-2 cells for PEPT1 and SKPT cells for PEPT2, valganciclovir inhibited glycylsarcosine transport mediated by PEPT1 and PEPT2 with K(i) values (inhibition constant) of 1.68+/-0.30 and 0.043+/- 0.005 mM, respectively. The inhibition by valganciclovir was competitive in both cases [1].in vivo: 37 patients were enrolled; 19 patients received treatment with VGV and 18 patients received treatment with GCV. The VGV was not inferior in efficacy to GCV as pre-emptive therapy, with rates of viral clearance at 28 days of 89.5% and 83%, respectively (P-value for non-inferiority = 0.030). Toxicities were similar between the 2 arms. No patients developed CMV disease [2]. Patients being treated with an alemtuzumab-containing regimen received prophylaxis with either valaciclovir 500 mg orally daily orvalganciclovir 450 mg orally twice daily. None of the 20 patients randomized to valganciclovir experienced CMV reactivation (P = .004) [3].
物理化学性质:
CAS号:175865-60-8
常用中文名:缬更昔洛韦
常用英文名:Valganciclovir
分子式:C14H22N6O5
分子量:354.362
密度:1.6±0.1 g/cm3
沸点:629.1±65.0 °C at 760 mmHg
熔点:N/A
闪点:334.3±34.3 °C
储存条件:室温,干燥

供应商信息

达阳化工(杭州)有限公司 认证供应商

认证状态:已认证供应商
商品数:50185件
电话:+86571-88938639
地址:浙江省杭州市西湖区文三路259号2栋9楼
地区: 浙江省 杭州市 西湖区
联系人:王小姐
联系人电话:+86-571-8893-8639
邮件:enquiry@dycnchem.com
网址:http://www.dycnchem.com
主要市场:Mainly in Southeast Asia and European and American markets
年贸易额:10 to 20 million USD
外贸占销售比例:90%
主要合作伙伴:
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参考价格:$132/50mg
其他供应商价格:
2024-07-15 缬更昔洛韦
价格:需询单
2022-03-04 缬更昔洛韦盐酸盐 d8
价格:¥40648.0
2024-01-09 Valganciclovir
价格:$需询单

查看所有价格,请点击缬更昔洛韦价格