Amlodipine besilate
更新时间：2022-03-05 17:04:13
采购访问：40次
| 常用名 | 苯磺酸氨氯地平 | CAS号 | 111470-99-6 |
|---|---|---|---|
| 价格 | $需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： Amlodipine besylate is a long-acting calcium channel blocker.Target: Calcium ChannelAmlodipine is a dihydropyridine calcium antagonist (calcium ion antagonist or slow-channel blocker) that inhibits the movement of calcium ions into vascular smooth muscle cells and cardiac muscle cells. Experimental data suggest amlodipine binds to both dihydropyridine and nondihydropyridine binding sites. The contractile processes of cardiac muscle and vascular smooth muscle are dependent upon the movement of extracellular calcium ions into these cells through specific ion channels. Amlodipine inhibits calcium ion influx across cell membranes selectively, with a greater effect on vascular smooth muscle cells than on cardiac muscle cells. Negative inotropic effects, or decreased heart muscle contractility, can be detected in vitro, but such effects have not been seen in intact animals at therapeutic doses. Serum calcium concentration is not affected by amlodipine. Within the physiologic pH range, amlodipine is an ionized compound (pKa = 8.6), and its interaction with the calcium channel receptor is characterized by a gradual rate of association and dissociation with the receptor binding site, resulting in a gradual onset of effect. Amlodipine is a peripheral arterial vasodilator that acts directly on vascular smooth muscle to cause a reduction in peripheral vascular resistance and reduction in blood pressure. From Wikipedia. 物理化学性质： CAS号：111470-99-6 常用中文名：苯磺酸氨氯地平 常用英文名：Amlodipine besylate 分子式：C26H31ClN2O8S 分子量：567.051 密度：1.227g/cm3 沸点：527.2ºC at 760 mmHg 熔点：199-201°C 闪点：272.6ºC 储存条件：Store at RT |
达阳化工（杭州）有限公司
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主要市场：Mainly in Southeast Asia and European and American markets
年贸易额：10 to 20 million USD
外贸占销售比例：90%
主要合作伙伴：
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：苯磺酸氨氯地平
- 价格： ￥159.9/1g ￥4201.9/100g ￥2078.9/25g ￥490.9/5g
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
- 江西瑞威尔生物科技有限公司
- 江西省 吉安市 峡江县
- 产品名：苯磺酸氨氯地平
- 价格： ￥600.0/200g ￥需询单/100mg ￥需询单/10g ￥需询单/100g
- 纯度：98.0%
- 备货期：1天
- 联系人：李经理
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参考价格：$92/10mM*1mLinDMSO