Coluracetam
更新时间：2022-01-28 12:36:48
采购访问：40次
| 常用名 | 考拉西坦 | CAS号 | 135463-81-9 |
|---|---|---|---|
| 价格 | $需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： Coluracetam(MKC-231) is a new choline uptake enhancer.IC50 value:Target:in vitro: MKC-231 (10(-10)-10(-6) moll) significantly increased high affinity choline uptake (HACU) when it was incubated with the hippocampal synaptosomes of ethylcholine mustard aziridinium ion (AF64A) treated rats, but not of normal rats. MKC-231 did not affect the AChE activity, [3H]- quinuclidinyl benzilate binding, and [3H]-pirenzepine binding [1].in vivo: Oral administration of MKC-231 (1-10 mg/kg) significantly improved the learning deficits in the Morris' water maze of AF64A-treated rats, but it did not produce any significant side effects, like tremor, salivation or hypothermia, which were observed in rats treated with high doses of tacrine [1]. In acute behavioral experiments, MKC-231 and THA had no significant effect on AF64A-induced memory deficits at any doses tested (0.3, 1.0 and 3.0 mg/kg), whereas Dup 996, at a dose of 1.0 mg/kg, significantly improved memory deficits. In chronic experiments, MKC-231 improved memory deficit at all doses tested (0.3, 1.0, or 3.0 mg/kg p.o., once daily for 11 days) and Dup 996 did so only at a dose of 3.0 mg/kg, whereas THA did not improve memory deficit at any doses tested [2]. 物理化学性质： CAS号：135463-81-9 常用中文名：考拉西坦 常用英文名：coluracetam 分子式：C19H23N3O3 分子量：341.404 密度：1.3±0.1 g/cm3 沸点：634.1±55.0 °C at 760 mmHg 熔点：225 °C 闪点：337.3±31.5 °C 储存条件：存放于惰性气体之中;避免空气 |
达阳化工（杭州）有限公司
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外贸占销售比例：90%
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- 产品名：N-(2,3-二甲基-5,6,7,8-四氢呋喃并[2,3-B]喹啉-4-基)-2-(2-氧代吡咯烷-1-基)乙酰胺
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：徐经理
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参考价格：￥585/250mg