常用名 | Necrostatin 2 S对映体 | CAS号 | 852391-20-9 |
---|---|---|---|
价格 | $需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg | 纯度 | 98.0% |
备货期 | 需询单 | 库存 | 询单 |
产品详情(用途,包装等)
用途: Necrostatin 2 is a potent necroptosis inhibitor with EC50 of 50 nM.IC50 Value: 50 nM (EC50) [1]Target: TNF-alphaNecrostatin 2 is a potent in vitro necroptosis inhibitors (exemplified by 1, EC50-0.05 uM) that also were efficacious in an animal model of ischemic stroke. Many Necroptosis inhibitor derivatives are designed for researchers.Necroptosis is a regulated caspase-independent cell death mechanism that results in morphological features resembling necrosis. It can be induced in a FADD-deficient variant of human Jurkat T cells treated with TNF-a. 5-(1H-Indol-3-ylmethyl)-2-thiohydantoins and 5-(1H-indol-3-ylmethyl)hydantoins were found to be potent necroptosis inhibitors (called necrostatins). 物理化学性质: CAS号:852391-20-9 常用中文名:Necrostatin 2 S对映体 常用英文名:Necrostatin 2 (S enantiomer) 分子式:C13H12ClN3O2 分子量:277.70600 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A 储存条件:2-8℃ |