5,5-Diphenylhydantoin
更新时间：2022-03-08 16:22:50
采购访问：39次
| 常用名 | 苯妥英 | CAS号 | 57-41-0 |
|---|---|---|---|
| 价格 | $需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： Phenytoin is an inactive voltage-gated sodium channel stabilizer.Target: Sodium ChannelPhenytoin is an antiepileptic drug. It is useful to treat partial seizures and generalized tonic-clonic seizures but not primary generalized seizures such as absence seizures or myoclonic seizures. Phenytoin is believed to protect against seizures by causing voltage-dependent block of voltage-gated sodium channels [1]. Phenytoin has low affinity for resting sodium channels at hyperpolarized membrane potentials [2]. When neurons are depolarized and the channels transition into the open and inactivated states, greater binding and block occur. The inhibitory potency is strongly use dependent, so that block accumulates with prolonged or repetitive activation, such as occurs during a seizure discharge. The blocking of sodium channels by phenytoin is of slow onset. The time course of fast sodium currents is therefore not altered in the presence of the drug and action potentials evoked by synaptic depolarizations of ordinary duration are not blocked. Thus phenytoin is able to selectively inhibit pathological hyperexcitability in epilepsy without unduly impairing ongoing activity. Phenytoin also blocks persistent sodium current and this may be of particular importance in seizure control. Phenytoin is a class 1b antiarrhythmic [3]. 物理化学性质： CAS号：57-41-0 常用中文名：苯妥英 常用英文名：phenytoin 分子式：C15H12N2O2 分子量：252.268 密度：1.3±0.1 g/cm3 沸点：464.0±55.0 °C at 760 mmHg 熔点：293-295 °C(lit.) 闪点：305.8±20.8 °C 储存条件：2-8°C |
达阳化工（杭州）有限公司
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- 上海市 上海市 普陀区
- 产品名：5,5-二苯基海因
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：徐经理
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参考价格：$66/10mM*1mLinDMSO