Dideoxyinosine
更新时间：2021-07-26 18:31:53
采购访问：36次
| 常用名 | 地达诺辛 | CAS号 | 69655-05-6 |
|---|---|---|---|
| 价格 | $需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： Didanosine(Videx) is a reverse transcriptase inhibitor with an IC50 of 0.49 μM.Target: NRTIs; HIVDidanosine is a dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase. Didanosine demonstrated linear pharmacokinetic behavior over the dose ranges of 0.4 to 16.5 mg/kg intravenously and 0.8 to 10.2 mg/kg orally. Bioavailability of didanosine when administered as a solution with an antacid was approximately 43% for doses from 0.8 to 10.2 mg/kg in patients with AIDS and advanced AIDS-related complex. Bioavailability of didanosine from the citrate-phosphate-buffered solution, the formulation currently used in phase II and expanded access studies, was comparable to the formulation used in the phase I trials [1]. ddI might be responsible for fulminant hepatitis in all three AIDS patients. This toxic effect may be added to the list of potential adverse events occurring during ddI therapy [2]. 物理化学性质： CAS号：69655-05-6 常用中文名：地达诺辛 常用英文名：2',3'-Dideoxyinosine 分子式：C10H12N4O3 分子量：236.227 密度：1.8±0.1 g/cm3 沸点：531.2±60.0 °C at 760 mmHg 熔点：193-195 °C 闪点：275.0±32.9 °C 储存条件：2-8°C |
达阳化工（杭州）有限公司
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主要市场：Mainly in Southeast Asia and European and American markets
年贸易额：10 to 20 million USD
外贸占销售比例：90%
主要合作伙伴：
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：2',3'-二脱氧肌苷
- 价格： ￥1969.9/1g ￥999.9/250mg ￥1599.9/500mg ￥399.9/50mg
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
- 上海阿摩尔生物科技有限公司
- 上海市 上海市 奉贤区
- 产品名：地达诺辛
- 价格： ￥需询单/1g ￥需询单/250mg ￥需询单/25g ￥需询单/50mg
- 纯度：98.0%
- 备货期：需询单
- 联系人：王汐瑶
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参考价格：￥179.4/1g