Naftifine hydrochloride
更新时间：2023-03-12 18:57:49
采购访问：36次
| 常用名 | 盐酸萘替芬 | CAS号 | 65473-14-5 |
|---|---|---|---|
| 价格 | $需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： Naftifine Hydrochloride is a synthetic, broad spectrum, antifungal agent.Target: AntifungalNaftifine exhibits an interesting in vitro spectrum of activity against dermatophytes (38 strains; minimal inhibitory concentration (MIC) range 0.1 to 0.2 mg/mL), aspergilli (6 strains; MIC range, 0.8 to 12.5 mg/mL), Sporothrix schenckii (2 strains; MICs, 0.8 and 1.5 mg/mL), and yeasts of the genus Candida (77 strains; MIC range, 1.5 to greater than 100 mg/mL) [1]. The MIC of naftifine for C. albicans Δ63 is 100 mg/L in Sabouraud medium (initial pH 6.5). Naftifine (50 mg/L) gives greater than 99% inhibition of sterol biosynthesis both in whole cells and in cell extracts of C. albicans. The primary action of naftifine appears to be the blocking of fungal squalene epoxidation [2].Naftifine HCl 2% cream results in clinical cure rate and clinical success rate of 33% and 84% after treatment for 4 weeks, and week 2 efficacy response rates in Naftifine HCl 2% subjects are all lower than at week 4 but are significantly higher than week 2 vehicle-treated counterparts [3]. Naftifine causes interruption of fungal ergosterol synthesis and accumulation of squalene in fungal organisms. Naftifine also has demonstrated anti-inflammatory properties such as a reduction in superoxide production and a reduction in polymorphonuclear leukocyte chemotaxis/endothelial adhesion. Naftifine has shown good efficacy and safety for a variety of conditions and is a useful treatment that provides both antifungal action and relief of inflammatory signs and symptoms. Few adverse events have been noted with naftifine use, the most frequent being mild and transient burning, stinging, or itching in the application area [4]. 物理化学性质： CAS号：65473-14-5 常用中文名：盐酸萘替芬 常用英文名：Naftifine hydrochloride 分子式：C21H22ClN 分子量：323.859 密度：N/A 沸点：440.1ºC at 760 mmHg 熔点：172-175ºC 闪点：194.4ºC 储存条件：-20?C Freezer |
达阳化工（杭州）有限公司
认证状态：已认证供应商
商品数：50185件
电话：+86571-88938639
地址：浙江省杭州市西湖区文三路259号2栋9楼
地区： 浙江省 杭州市 西湖区
联系人：王小姐
联系人电话：+86-571-8893-8639
邮件：enquiry@dycnchem.com
网址：http://www.dycnchem.com
主要市场：Mainly in Southeast Asia and European and American markets
年贸易额：10 to 20 million USD
外贸占销售比例：90%
主要合作伙伴：
- 上海化源生化科技有限公司
- 上海市 上海市 普陀区
- 产品名：盐酸萘替芬
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：化源
- 上海吉至生化科技有限公司
- 上海市 上海市 奉贤区
- 产品名：盐酸萘替芬
- 价格： ￥908.0/5g ￥2688.0/25g ￥378.0/1g
- 纯度：99.0%
- 备货期：需询单
- 联系人：刘佳
- 上海源溪生物科技有限公司
- 上海市 上海市 浦东新区
- 产品名：AW 105843
- 价格： ￥需询单/1g
- 纯度：98.9%
- 备货期：1天
- 联系人：赖经理
- 上海脉铂医药科技有限公司
- 上海市 上海市 嘉定区
- 产品名：Naftifine HCl
- 价格： ￥889.0/500mg ￥389.0/50mg ￥需询单/1g ￥需询单/1g
- 纯度：98.0%
- 备货期：2天
- 联系人：李先生
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：盐酸萘替芬
- 价格： ￥407.9/1g ￥1596.9/5g ￥2780.9/25g ￥需询单/1g
- 纯度：99.0%
- 备货期：1天
- 联系人：阿拉丁
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参考价格：$238/10mM*1mLinEthanol