Tolterodine
更新时间：2022-02-12 18:32:09
采购访问：22次
| 常用名 | 托特罗定 | CAS号 | 124937-51-5 |
|---|---|---|---|
| 价格 | $需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： Tolterodine(PNU-200583) is a potent muscarinic receptor antagonists that show selectivity for the urinary bladder over salivary glands in vivo. IC50 Value:Target: mAChRin vitro: Carbachol-induced contractions of isolated guinea pig bladder were effectively inhibited by tolterodine (IC50 14 nM) and 5-HM (IC50 5.7 nM). The IC50 values were in the microM range and the antimuscarinic potency of tolterodine was 27, 200 and 370-485 times higher, respectively, than its potency in blocking histamine receptors, alpha-adrenoceptors and calcium channels. The active metabolite, 5-HM, was >900 times less potent at these sites than at bladder muscarinic receptors [1].in vivo: Tolterodine was extensively metabolized in vivo [2]. In the passive-avoidance test, tolterodine at 1 or 3 mg/kg had no effect on memory; the latency to cross and percentage of animals crossing were comparable to controls. In contrast, scopolamine induced a memory deficit; the latency to cross was decreased, and the number of animals crossing was increased [3]. 物理化学性质： CAS号：124937-51-5 常用中文名：托特罗定 常用英文名：Tolterodine-L-tartrate 分子式：C22H31NO 分子量：325.488 密度：1.0±0.1 g/cm3 沸点：442.2±45.0 °C at 760 mmHg 熔点：N/A 闪点：192.1±27.4 °C 储存条件：-20°C Freezer |
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- 产品名：Tolterodine-L-tartrate
- 价格： ￥770.0/5mg ￥3552.0/25mg ￥需询单/1g ￥需询单/1g
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
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参考价格：$106/10mM*1mLinDMSO