Prinaberel
更新时间：2025-08-14 09:47:51
采购访问：25次
| 常用名 | 普林贝瑞 | CAS号 | 524684-52-4 |
|---|---|---|---|
| 价格 | $需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： Prinaberel(ERB-041) is a potent and selective ERbeta agonist; being >200-fold selective for ERbeta.IC50 value:Target: ERbeta agonistin vitro: Treatment with ERβ selective estrogen agonists liquiritigenin and ERB-041 reduced the ability to invade a reconstituted basement membrane and to migrate in response to the cellular stimulus [1]. Pretreatment the PMs with ERB-041 resulted in a significant inhibition of LPS-induced iNOS expression and NF-kappaB activation by preventing its nuclear translocation [3].in vivo: Tumor numbers and volume were reduced by 60% and 84%, respectively, in the Erb-041-treated group as compared with UVB (alone) control. This inhibition in tumorigenesis was accompanied by the decrease in proliferating cell nuclear antigen (PCNA), cyclin D1, VEGF, and CD31, and an increase in apoptosis [2]. 物理化学性质： CAS号：524684-52-4 常用中文名：普林贝瑞 常用英文名：Prinaberel 分子式：C15H10FNO3 分子量：271.243 密度：1.4±0.1 g/cm3 沸点：451.6±45.0 °C at 760 mmHg 熔点：250-252ºC 闪点：226.9±28.7 °C 储存条件：2-8℃ |
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