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Tripelennamine hydrochloride TOP1 supplier

更新时间:2023-10-17 11:32:03 采购访问:34次

常用名 盐酸曲吡那敏 CAS号 154-69-8
价格 $需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg 纯度 98.0%
备货期 需询单 库存 询单
 产品详情(用途,包装等)
用途:
Tripelennamine Hcl, a H1-receptor antagonist, is a psychoactive drug and member of the pyridine andethylenediamine classes that is used as an antipruritic and first-generation antihistamine.IC50 Value:Target: Histamine H1 receptorTripelennamine can be used in the treatment of asthma, hay fever, rhinitus and urticaria.in vitro: Arterial and mixed venous blood-gas and pH measurements were made at rest before and after saline or drug administration and during incremental exercise leading to maximal exertion at 14 m/s on 3.5% uphill grade for 120 s. Galloping at this workload elicited maximal heart rate and induced exercise-induced pulmonary hemorrhage in all horses in both treatments, thereby indicating that capillary stress failure-related pulmonary injury had occurred [1].in vivo: The data obtained (median and range in brackets) in camels and horses, respectively, were as follows: the terminal elimination half-lives were 2.39 (1.91-6.54) and 2.08 (1.31-5.65) h, total body clearances were 0.97 (0.82-1.42) and 0.84 (0.64-1.17)L/h/kg. The volumes of distribution at steady state were 2.87 (1.59-6.67) and 1.69 (1.18-3.50) L/kg, the volumes of the central compartment of the two compartment pharmacokinetic model were 1.75 (0.68-2.27) and 1.06 (0.91-2.20) L/kg [2]. After intramuscular administration of 50 or 100 mg tripelennamine, mean plasma concentrations at 30 minutes were 105 and 194 ng/ml, respectively, and mean plasma t1/2 values were 2.9 and 4.4 hours, respectively [3].
物理化学性质:
CAS号:154-69-8
常用中文名:盐酸曲吡那敏
常用英文名:Tripelennamine (hydrochloride)
分子式:C16H22ClN3
分子量:291.81900
密度:1.20
沸点:387.8ºC at 760 mmHg
熔点:192-193ºC
闪点:188.3ºC
储存条件:Refrigerator

供应商信息

达阳化工(杭州)有限公司 认证供应商

认证状态:已认证供应商
商品数:48443件
电话:+86571-88938639
地址:浙江省杭州市西湖区文三路259号2栋9楼
地区: 浙江省 杭州市 西湖区
联系人:王小姐
联系人电话:+86-571-8893-8639
邮件:enquiry@dycnchem.com
网址:http://www.dycnchem.com
主要市场:Mainly in Southeast Asia and European and American markets
年贸易额:10 to 20 million USD
外贸占销售比例:90%
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参考价格:¥234/1g
其他供应商价格:
2022-03-04 盐酸曲吡那敏
价格:¥61.9
2024-07-15 盐酸曲吡那敏
价格:需询单
2021-02-06 Tripelennamine HCl
价格:¥659.0

查看所有价格,请点击盐酸曲吡那敏价格