| 常用名 | (T-4)-[(1E,6E)-1,7-双[4-(二甲基氨基)苯基]-1,6-庚二烯-3,5-dionato-κO3,κO5]二氟硼 | CAS号 | 1193447-34-5 |
|---|---|---|---|
| 价格 | $需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情(用途,包装等)
用途: CRANAD-2 is a difluoroboron-derivatized curcumins as near-infrared probe for in vivo detection of amyloid-beta deposits. Upon interacting with Abeta aggregates, CRANAD-2 undergoes a range of changes, which include a 70-fold fluorescence intensity increase, a 90 nm blue shift (from 805 to 715 nm), and a large increase in quantum yield. Moreover, this probe also shows a high affinity for Abeta aggregates (K(d) = 38.0 nM), a reasonable log P value (log P = 3), considerable stability in serum, and a weak interaction with albumin. After intravenous injection of this probe, 19-month-old Tg2576 mice exhibited significantly higher relative signal than that of the control mice over the same period of time. 物理化学性质: CAS号:1193447-34-5 常用中文名:(T-4)-[(1E,6E)-1,7-双[4-(二甲基氨基)苯基]-1,6-庚二烯-3,5-dionato-κO3,κO5]二氟硼 常用英文名:CRANAD-2 分子式:C23H25BF2N2O2 分子量:410.26500 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A 储存条件:2-8°C |